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Monica M Bertagnolli Selected Research

Celecoxib (Celebrex)

1/2018Chemopreventive Efficacy of the Cyclooxygenase-2 (Cox-2) Inhibitor, Celecoxib, Is Predicted by Adenoma Expression of Cox-2 and 15-PGDH.
4/2015Celecoxib inhibits early cutaneous wound healing.
2/2014Lack of anti-tumor activity with the β-catenin expression inhibitor EZN-3892 in the C57BL/6J Min/+ model of intestinal carcinogenesis.
12/2013Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
1/2012The influence of UGT1A6 variants and aspirin use in a randomized trial of celecoxib for prevention of colorectal adenoma.
8/2011C-reactive protein and risk of colorectal adenoma according to celecoxib treatment.
6/2010Persistent cyclooxygenase-2 inhibition downregulates NF-{kappa}B, resulting in chronic intestinal inflammation in the min/+ mouse model of colon tumorigenesis.
5/2010Statin use and colorectal adenoma risk: results from the adenoma prevention with celecoxib trial.
3/2010Chronic cyclooxygenase-2 inhibition promotes myofibroblast-associated intestinal fibrosis.
6/200915-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.
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Monica M Bertagnolli Research Topics

Disease

56Neoplasms (Cancer)
01/2022 - 04/2003
23Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 11/2002
19Adenoma (Adenomas)
01/2018 - 02/2005
15Colonic Neoplasms (Colon Cancer)
01/2017 - 12/2004
10Leukemia
01/2017 - 01/2004
10Carcinogenesis
02/2014 - 12/2004
7Microsatellite Instability
10/2019 - 01/2004
6Sarcoma (Soft Tissue Sarcoma)
02/2018 - 09/2009
5Inflammation (Inflammations)
04/2015 - 05/2007
4Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2018 - 05/2006
4Aggressive Fibromatosis (Desmoid)
01/2018 - 01/2012
4Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
01/2014 - 11/2002
3Adenocarcinoma
09/2015 - 08/2011
3Carcinoma (Carcinomatosis)
12/2013 - 03/2007
2Breast Neoplasms (Breast Cancer)
01/2020 - 09/2009
2Leiomyosarcoma
01/2018 - 05/2017
2Liposarcoma
01/2018 - 05/2017
2Stomach Neoplasms (Stomach Cancer)
09/2015 - 06/2015
2Wounds and Injuries (Trauma)
04/2015 - 05/2013
2Cardiovascular Diseases (Cardiovascular Disease)
08/2011 - 05/2010
2Fibrosis (Cirrhosis)
06/2010 - 03/2010
2Arthritis (Polyarthritis)
04/2008 - 06/2006
1Neutropenia
11/2019
1Thrombocytopenia (Thrombopenia)
11/2019
1Hepatocellular Carcinoma (Hepatoma)
11/2019
1Liver Neoplasms (Liver Cancer)
11/2019
1Neoplasm Metastasis (Metastasis)
02/2018
1Fibroma (Fibromatosis)
09/2017
1Angiosarcoma of the breast
01/2017
1Melanoma (Melanoma, Malignant)
11/2016

Drug/Important Bio-Agent (IBA)

18Celecoxib (Celebrex)FDA Link
01/2018 - 10/2004
12Fluorouracil (Carac)FDA LinkGeneric
01/2021 - 03/2009
11Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2018 - 06/2004
10Biomarkers (Surrogate Marker)IBA
12/2020 - 06/2008
10Pharmaceutical PreparationsIBA
12/2018 - 04/2009
10Leucovorin (Folinic Acid)FDA Link
01/2017 - 03/2009
9Irinotecan (Camptosar)FDA LinkGeneric
01/2021 - 03/2009
9Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
04/2015 - 10/2004
7Proteins (Proteins, Gene)FDA Link
10/2013 - 11/2002
6Cetuximab (Erbitux)FDA Link
01/2022 - 12/2009
5Bevacizumab (Avastin)FDA Link
01/2022 - 12/2013
5Biological ProductsIBA
01/2017 - 01/2007
5Calcibiotic Root Canal SealerIBA
02/2016 - 01/2004
5Phosphotransferases (Kinase)IBA
12/2013 - 10/2004
4DNA (Deoxyribonucleic Acid)IBA
10/2019 - 04/2009
4ErbB Receptors (EGF Receptor)IBA
11/2016 - 10/2004
3Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2021 - 10/2013
3EnzymesIBA
01/2018 - 05/2007
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2018 - 08/2011
3CateninsIBA
09/2017 - 04/2012
3Imatinib Mesylate (Gleevec)FDA Link
08/2015 - 11/2008
3Dinoprostone (PGE2)FDA Link
04/2015 - 10/2004
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
04/2012 - 10/2004
3Transforming Growth Factor beta (TGF-beta)IBA
06/2010 - 12/2004
3ProstaglandinsIBA
06/2010 - 01/2007
2RNA (Ribonucleic Acid)IBA
01/2022 - 11/2016
2Sorafenib (BAY 43-9006)FDA Link
11/2019 - 01/2018
2Doxorubicin (Adriamycin)FDA LinkGeneric
11/2019 - 02/2009
2hypoiodous acid (HOI)IBA
01/2018 - 05/2017
215-hydroxyprostaglandin dehydrogenaseIBA
01/2018 - 06/2009
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018 - 02/2012
2Estrogen ReceptorsIBA
01/2014 - 03/2007
2Estradiol (Delestrogen)FDA LinkGeneric
01/2014 - 03/2005
2Estrogens (Estrogen)FDA Link
01/2014 - 03/2005
2Phosphatidylinositols (Phosphatidylinositol)IBA
12/2013 - 10/2004
2ParaffinIBA
05/2013 - 03/2009
2EdrecolomabIBA
05/2013 - 08/2011
2Tyrosine (L-Tyrosine)FDA Link
04/2012 - 02/2005
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2011 - 05/2010
2Prostaglandins EIBA
06/2010 - 06/2009
2beta CateninIBA
06/2008 - 02/2005
2Estrogen Receptor alphaIBA
06/2008 - 03/2007
2Estrogen Receptor betaIBA
03/2007 - 03/2005
2Cadherins (E-Cadherin)IBA
02/2006 - 02/2005
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
10/2004 - 11/2003
1LuciferasesIBA
01/2021
1B7-H1 AntigenIBA
01/2021
1Investigational DrugsIBA
01/2020
1Genetic Markers (Genetic Marker)IBA
10/2019
1Tyrosine Kinase InhibitorsIBA
01/2018
1Oxidoreductases (Dehydrogenase)IBA
01/2018
1Thymidylate SynthaseIBA
01/2017
1Monoclonal AntibodiesIBA
01/2017
1Conditioned Culture MediaIBA
11/2016
1Transforming Growth Factor alpha (TGF-alpha)IBA
11/2016
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
08/2015

Therapy/Procedure

12Drug Therapy (Chemotherapy)
01/2022 - 06/2004
12Therapeutics
01/2020 - 05/2006
8Chemoprevention
01/2018 - 01/2005
7Adjuvant Chemotherapy
12/2013 - 03/2009
4Radiotherapy
01/2017 - 09/2009
3Aftercare (After-Treatment)
06/2010 - 12/2004
2Cytoreduction Surgical Procedures
01/2018 - 02/2010
2Gastrectomy
09/2015 - 06/2015
1Immunotherapy
01/2021
1Precision Medicine
12/2018
1Surgical Amputation (Amputations)
02/2018
1Biological Therapy
01/2017
1Lymph Node Excision (Lymph Node Dissection)
09/2015
1Neoadjuvant Therapy
06/2015